Test Description

The testing options are as follows:

CoGenesis® Alzheimer’s Disease (AD)

• The CoGenesis® AD test covers 6 high-risk genes associated with early-onset Alzheimer’s disease. It is specifically designed for individuals already diagnosed with early-onset Alzheimer’s disease, those who suspect they may have early-onset AD, or individuals with family members affected by early-onset AD.

CoGenesis® APOE

• The CoGenesis® APOE Genetic Test only covers the APOE gene, a high-risk gene associated with late-onset Alzheimer’s disease. It is specifically designed for individuals already diagnosed with late-onset AD, those who suspect they may have late-onset AD, or individuals with family members affected by late-onset AD.

What is the purpose of this genetic test?

• Understanding genetic variations in Alzheimer’s disease through our testing results can help assess the inherited risk of early-onset or late-onset Alzheimer’s disease.
• Knowing the possible disease-causing genes can assist doctors in formulating personalized treatments. Different genetic variations can affect the efficacy and safety of medications. For example, individuals with the APOE4 genetic variant may have a risk of brain swelling when taking the new drug Aducanumab.
• Approximately 50% of early-onset Alzheimer’s disease patients have a family history of the disease. Therefore, individuals with family members affected by Alzheimer’s should consider whether they have a chance of carrying genetic variations associated with a high risk of Alzheimer’s disease.

Covered Genes

APP, PSEN1, PSEN2, APOE, TREM2, MAPT

Sample collection method

You can make an appointment immediately by following the instructions below and come to the Hong Kong Well Clinic to have your saliva or blood sample collected.

Processing and Delivery of Test Reports

• Once our laboratory receives your saliva or blood sample and confirms that the sample meets the quality standards for testing, you will receive an email notification. You can also track the progress of the testing on this online platform. The estimated time for the report will be counted from the point when the sample meets the testing standards.
• The expected turnaround time for this test is 4 working weeks.
• Once your test report is ready, you will receive an email notification. The report is usually delivered electronically on this online platform, where you can log in to view and download it. If you have any specific requirements for delivery, please contact our customer service representative after placing the order.