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Positron Emission Tomography-Computed Tomography (PET-CT) is one of the most advanced medical imaging technologies available today. It seamlessly combines the functional imaging of a PET scan with the precise anatomical detail of a CT scan in a single machine. While the CT provides a clear structural map of internal organs, the PET scan detects the metabolic activity of cells, allowing doctors to pinpoint areas of abnormal cellular activity with exceptional accuracy.
Before the scan, a small amount of a radioactive tracer (most commonly FDG, a form of glucose) is injected into the body. Because cancer cells grow rapidly and consume much more glucose than normal cells, they absorb high amounts of the tracer. These areas appear as bright “hot spots” on the PET-CT images, making it an invaluable tool for early cancer detection and precise localization.
Yes, a PET-CT involves radiation from both the injected tracer and the CT scan. However, we use strict, medical-grade safety doses. The radioactive tracer has a very short half-life and decays quickly. Under professional supervision, the immense clinical benefits of a precise diagnosis far outweigh the minimal radiation risks.
FDG is structurally very similar to the natural glucose your body consumes daily, making allergic reactions or side effects extremely rare. Drinking plenty of water and urinating frequently after the exam will help flush the remaining tracer from your system, usually within a day.
PET-CT relies heavily on cellular absorption of glucose (the FDG tracer). If your blood sugar is too high before the scan, the natural glucose in your blood will compete with the tracer to enter the cells. This can reduce the tracer uptake in tumors, resulting in blurry images or potential misdiagnosis.
While the actual scanning time in the machine is only 20 to 30 minutes, you should expect to spend about 2 to 3 hours at the clinic. This accounts for registration, blood sugar testing, the injection, the 1-hour resting period for tracer uptake, and the scan itself.
For precautionary safety, although the residual radiation in your body is very low and decreases rapidly, we advise avoiding close or prolonged contact with pregnant women and infants for about 8 to 12 hours following the completion of your scan.
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