Price：$2,300
Understand Hereditary Alzheimer's Disease Risk
Alzheimer’s disease genetic testing focuses on gene variants associated with Alzheimer’s disease. With interpretation by a doctor, results may help clarify possible causes, shorten the search for diagnostic clues and support personalised follow-up planning.
Alzheimer's Disease and Genetics
Alzheimer’s disease heritability is estimated at 60-80%. Carrying one APOE4 variant may increase risk by 3 to 4 times, while carrying two related variants may increase risk by 9 to 15 times.
Alzheimer’s disease is not only a condition of older age. Around 35-60% of early-onset Alzheimer’s disease patients have a family history, and early-onset cases can begin before the age of 40.
Who Should Consider It?
People diagnosed with Alzheimer’s disease: to understand possible causes and support personalised treatment planning by doctors. People suspected of having Alzheimer’s disease: to help doctors clarify possible causes more efficiently. People with a family history of Alzheimer’s disease: to understand whether they carry high-risk variants.
What the Test Covers
The test covers 6 common Alzheimer’s disease-related genes: APP, PSEN1, PSEN2, APOE, TREM2 and MAPT. An APOE genetic test option focuses on the common Alzheimer’s disease-related gene APOE.
Genetic results should be clinically interpreted by relevant medical professionals together with medical history, cognitive assessment and other investigations.
How Results May Help
Results are intended to provide hereditary risk information for doctors rather than act as a standalone diagnosis. The report may support assessment of early- or late-onset Alzheimer’s disease risk and help families with relevant history understand their own risk more clearly.
Testing Accuracy
Technical information indicates 99.9% accuracy for DNA sequencing and >99% accuracy for SNP and indel variant calling, with external quality assurance through GenQA / UK NEQAS. Variant classification may change as medical knowledge develops, and not all variants are necessarily included in the report.
Enquiry and Booking
If you or your family would like to understand Alzheimer’s disease-related hereditary risk, contact Well Clinic for enquiry.
Contact Us
WhatsApp / WeChat: +852 5292 0089
Address: Room B, 24/F, Lee Tung Building, 9 Li Yuen Street East, Central, Hong Kong